Tell us what do you think about our website?

BICS Logo

WELCOME TO THE BICS STUDY

A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease. Bisoprolol in COPD study (BICS)

What is BICS?

BICS is a research study into the treatment of COPD. In the BICS study we are trying to find out if flare-ups of COPD can be prevented by using a tablet called bisoprolol. Bisoprolol is a beta-blocker that has been widely used for a long time to treat heart problems, but it now seems that bisoprolol might also reduce flare ups of COPD regardless of heart problems.

To find out if bisoprolol reduces the number of flare ups we are comparing the effects of bisoprolol against the effects of a placebo ‘dummy treatment’, which looks like the genuine medicine but contains no active ingredient.

Half of the people who take part in the BICS study will receive bisoprolol tablets and half will receive placebo tablets. People in the study will take the bisoprolol or placebo tablets for 12 months. During this 12 month period we will count how many flare-ups people have and then compare the numbers in each group.

We aim to recruit 1576 people with COPD into the BICS study.
placeholder

Can I take part?

We are recruiting patients at hospitals and GP practices across the UK. You can see the locations of these in the section of this website "where can I take part". More locations will be added as the study progresses.

Patients with COPD who are aged 40 years or older, and who have had two COPD flare-ups in the past year are eligible to take part. If you would like to take part or have any questions about the study, you can contact us using the form below or by telephoning 01224 438178.

placeholder

If you are interested in taking part, or have any questions?

CONTACT US

Where can I take part?

Aberdeen

Key people:

Investigator:

  • Dr David Miller

Address:

Respiratory Unit, Clinic C
Aberdeen Royal Infirmary
Aberdeen
AB25 2ZN
Aintree University Hospital

Key people:

Investigator:

  • Dr Paul Walker

Address:

Aintree University Hospital
Longmoor Lane
Liverpool
L9 7AL

Key people:

Investigator:

  • Dr Tony De Soyza

Address:

Sir William Leech Centre for Lung Research
Freeman Hospital
High Heaton
Newcastle upon Tyne
NE7 7DN
South Tyneside NHS Foundation Trust

Key people:

Investigator:

  • Dr Liz Fuller

Address:

Respiratory Research based on
Oncology and Haematology Day Unit
South Tyneside District Hospital
Harton Lane, South Shields, Tyne & Wear
NE34 0PL
Castlegate and Derwent Surgery

Key people:

Investigator:

  • Dr Mary Philipsz

Address:

Cockermouth Health Centre
Isel Road
Cockermouth
CA13 9HT
Vauxhall Primary Health Care

Key people:

Investigator:

  • Dr David Lewis

Address:

Vauxhall Primary Health Care
Limekiln Lane
Vauxhall
Liverpool
L5 8XR
Queen Square Medical Practice

Key people:

Investigator:

  • Dr Patrick Haslam

Address:

Queen Square Medical Practice
Queen Square Surgery
2 Queen Square
Lancaster
LA1 1RP
Alnwick Medical Practice

Key people:

Investigator:

  • Dr Graham Syers

Address:

Infirmary Close
Alnwick
Northumberland
NE66 2NL
Birmingham QEH

Key people:

Investigator:

  • Dr Simon Gompertz

Address:

Area 2, Level 7 - Respiratory
Queen Elizabeth Hospital Birmingham
Mindelsohn Way
Edgbaston, Birmingham
B15 2GW
Heartlands Hospital, Birmingham

Key people:

Investigator:

  • Dr Alice Turner

Address:

Respiratory Medicine
Heartlands Hospital
Bordesley Green East
Birmingham
B9 5SS
Basildon and Thurrock University Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Kirsten Wadsworth

Address:

Nethermayne
Basildon
Essex
SS16 5NL
Bedford Hospital NHS Trust

Key people:

Investigator:

  • Dr Mohammed Azher

Address:

Bedford Hospital NHS Trust
South Wing
Kempston Road
Bedford
MK42 9DJ
Blackpool Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Tarek Saba

Address:

Blackpool Victoria Hospital
Whinney Heys Road
Blackpool
Lancashire
FY3 8NR
Bradford Teaching Hospitals NHS Foundation Trust - coming soon

Key people:

Investigator:

  • Dr Dinesh Saralaya

Address:

Bradford Royal infirmary
Duckworth Lane
Bradford
BD9 6RL
Hull and East Yorkshire NHS Trust - coming soon

Key people:

Investigator:

  • Prof Alyn Morice

Address:

Castle Hill Hospital
Castle Road
Cottingham
HU16 5JQ
County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

  • Dr Peter Cook

Address:

University Hospital of North Durham
North Road
Durham
DH1 5TW
Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust - coming soon

Key people:

Investigator:

  • Dr Trevor Rogers

Address:

Doncaster Royal Infirmary
Thorne Road
Doncaster
DN2 5LT
County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

  • Dr Pradip De

Address:

Darlington Memorial Hospital
Hollyhurst Road
Darlington
DL3 6HX
East and North Herts NHS Trust - coming soon

Key people:

Investigator:

  • Prof Thida Win

Address:

Lister Hospital
Coreys Mill Lane
Stevenage
SG1 4AB
East Lancashire NHS Trust

Key people:

Investigator:

  • Dr Iain Crossingham

Address:

Royal Blackburn Hospital
Haslingden Road
Blackburn
Lancashire
BB2 3HH
NHS Greater Glasgow and Clyde

Key people:

Investigator:

  • Prof Rekha Chaudhuri

Address:

Gartnavel General Hospital
1053 Great Western Road
Glasgow
G12 OYN
Gateshead Health NHS Foundation Trust

Key people:

Investigator:

  • Dr Robert Allcock

Address:

Queen Elizabeth Hospital
Queen Elizabeth Avenue
Gateshead
NE9 6SX
Taunton and Somerset NHS Foundation Trust

Key people:

Investigator:

  • Dr Robert Stone

Address:

Musgrove Park Hospital
Taunton
Somerset
TA1 5DA
NHS Lanarkshire

Key people:

Investigator:

  • Dr Manish Patel

Address:

Wishaw General Hospital
50 Netherton Street
Wishaw
ML2 0DP
Norfolk and Norwich University Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Prof Andrew Wilson

Address:

Norfolk and Norwich University Hospital
Colney Lane
Norwich
NR4 7UY
Northumbria Healthcare NHS Foundation Trust

Key people:

Investigator:

  • Dr Stephen Bourke

Address:

North Tyneside General Hospital
Rake Lane
Tyne and Wear
North Shields
NE29 8NH
Royal Devon and Exeter NHS Foundation Trust - coming soon

Key people:

Investigator:

  • Dr Thomas Burden

Address:

Royal Devon and Exeter Hospital
Barrack Road
Exeter
EX2 5DW
NHS Lothian - coming soon

Key people:

Investigator:

  • Dr Gourab Choudhury

Address:

Royal Infirmary of Edinburgh
51 Little France Crescent
Old Keith Road
Edinburgh
EH16 4SA
South Tees Hospitals NHS Foundation Trust - coming soon

Key people:

Investigator:

  • Dr Rehan Mustafa

Address:

James Cook University Hospital
Marton Road
Middlesborough
TS4 3BW
North Tees and Hartlepool NHS Foundation Trust

Key people:

Investigator:

  • Dr Ben Prudon

Address:

University Hospital of North Tees
Hardwick
Stockton on Tees
TS19 8PE
University Hospitals Plymouth NHS Trust

Key people:

Investigator:

  • Dr Neil Ward

Address:

Derriford Hospital
Plymouth
Devon
PL6 8DH
University Hospitals of Derby and Burton NHS Foundation Trust

Key people:

Investigator:

  • Uttam Nanda

Address:

Queens Hospital
Belvedere Road
Burton Upon Trent
Staffordshire
DE13 0RB
University Hospitals of Morecambe Bay NHS Foundation Trust

Key people:

Investigator:

  • Dr Mark Wilkinson

Address:

Royal Lancaster Infirmary
Ashton Road
Lancaster
LA1 4RP
Wirral University Teaching Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr David Tarpey

Address:

Arrowe Park Hospital
Arrowe Park Road
Birkenhead
Wirral
CH49 5PE
Worcestershire Acute Hospitals NHS Trust - coming soon

Key people:

Investigator:

  • Dr Sarah Deacon

Address:

Worcestershire Royal Hospital
Charles Hastings Way
Worcester
WR5 1DD
Yeovil District Hospital NHS Foundation Trust - coming soon

Key people:

Investigator:

  • Dr Phil Raines

Address:

Yeovil District Hospital
Higher Kingston
Yeovil
BA21 4AT
Guide Post Medical Group

Key people:

Investigator:

  • Dr Catherine Bromham

Address:

North Parade
Choppington
Northumberland
NE62 5RA
Ash Trees Surgery

Key people:

Investigator:

  • Dr Harinder Mehta

Address:

Ash Trees Surgery
Carnforth
LA5 9JU
Axbridge and Wedmore Medical Practice

Key people:

Investigator:

  • Dr Ewart Jackson-Voyzey

Address:

Houlgate Way
Axbridge
Somerset
BS26 2BJ
Bay Medical Group

Key people:

Investigator:

  • Dr Russell Kelton

Address:

Heysham Primary Care Centre
Middleton Way
Heysham
LA3 2LE
Belford Medical Practice

Key people:

Investigator:

  • Dr Sebastian Moss

Address:

Croft Field
Belford
NE70 7ER
Bishopgate Medical Centre

Key people:

Investigator:

  • Dr Ian Bremner

Address:

178 Newgate Street
Bishop Auckland
County Durham
DL14 7EJ
Branch End Surgery - coming soon

Key people:

Investigator:

  • Dr Farzan Kamali

Address:

Main Road
Stocksfield
Northumberland
NE43 7LL
Burn Brae Medical Group - coming soon

Key people:

Investigator:

  • Dr Nick Hargreaves

Address:

Hexham Primary Care Centre
Corbridge Road
Hexham
NE46 1QJ
Carmel Medical Practice

Key people:

Investigator:

  • Prof Ahmet Fuat

Address:

Carmel Medical Practice
Nunnery Lane
Darlington County
Durham
DL3 8SQ
Cartmel Surgery

Key people:

Investigator:

  • Dr Julie Colclough

Address:

Haggs Lane
Cartmel
Grange-over-Sands
Cumbria
LA11 6PH
Cheviot Medical Group - coming soon

Key people:

Investigator:

  • Dr Liz Batley

Address:

Cheviot Primary Care Centre
Padgepool Place
Wooler
NE71 6BL
Claypath and University Medical Group

Key people:

Investigator:

  • Dr Stephen Dellar

Address:

26 Gilesgate
Durham
DH1 1QW
Corbridge Medical Group - coming soon

Key people:

Investigator:

  • Dr Tom Schatzberger

Address:

Corbridge Health Centre
Newcastle Road
Corbridge
Northumberland
NE45 5LG
Felton Surgery - coming soon

Key people:

Investigator:

  • Dr Lees Yvonne

Address:

Middle Farm
Main Street
Morpeth
NE65 9PR
Glendale Surgery

Key people:

Investigator:

  • Dr Saul Miller

Address:

Cheviot Primary Care Centre
Padgepool Place
Wooler
NE71 6BL
Haydon Bridge and Allendale Medical Practice - coming soon

Key people:

Investigator:

  • Dr Mary Henderson

Address:

Haydon Bridge Health Centre
North Bank
Haydon Bridge
Northumberland
NE47 6LA
Humshaugh and Wark Medical Group

Key people:

Investigator:

  • Dr Beth Gregory-Smith

Address:

1 East Lea
Humshaugh
Hexham
NE46 4BU
Lancaster Medical Practice

Key people:

Investigator:

  • Dr Michael Wong

Address:

Ashton Road
Rosebank
Lancaster
LA1 4JS
Leadgate Surgery

Key people:

Investigator:

  • Dr Gareth Forbes

Address:

George Ewen House
Watling Street
Consett
DH8 6DP
Leslie Surgery

Key people:

Investigator:

  • Dr Rajesh Muvva

Address:

Anderson Drive
Leslie
Glenrothes
KY6 3LQ
49 Marine Avenue Surgery - coming soon

Key people:

Investigator:

  • Dr Justine Norman

Address:

49 Marine Avenue Surgery
Whitley Bay
NE26 1NA
Oakenhurst Medical Practice

Key people:

Investigator:

  • Dr Amar Ali

Address:

Oakenhurst Medical Practice
Barbara Castle Way Health Centre
Simmons Street
Blackburn
BB2 1AX
Paxton Medical Group

Key people:

Investigator:

  • Dr David Lant

Address:

Claughton Medical Centre
161 Park Road
North Claughton
Birkenhead
CH41 0DD
Pelton and Fellrose Medical Group

Key people:

Investigator:

  • Dr Jose Miralles

Address:

Unit 1, The Lavender Centre
Pelton Lane
Chester le Street
County Durham
DH2 1HS
Pendle View Medical Centre

Key people:

Investigator:

  • Dr Rahul Thakur

Address:

47 Arthur Street
Brierfield
Nelson
BB9 5RZ
Railway Medical Group

Key people:

Investigator:

  • Dr Grace Watts

Address:

Railway Medical Group
Gatacre Street
Blyth
Northumberland
NE24 1HD
Skerne Medical Group

Key people:

Investigator:

  • Dr Ishbel Orla Whitehead

Address:

Harbinson House
Front Street
Sedgefield
Stockton-on-tees
TS21 3BN
Spring Terrace Health Centre - coming soon

Key people:

Investigator:

  • Dr Justine Norman

Address:

Spring Terrace health Centre
North Shields
Tyne and Wear
NE29 0HD
Station House Surgery

Key people:

Investigator:

  • Dr David Cowling

Address:

Station House Surgery
Station Road
Kendal
LA9 6SA
The Garth Surgery

Key people:

Investigator:

  • Dr Teik Goh

Address:

The Garth Surgery
Rectory Lane
Guisborough
TS14 7DJ
The Village Practice

Key people:

Investigator:

  • Dr Preeti Pandya

Address:

Thornton Medical Centre
Church Road
Thornton Cleveleys
Lancashire
FY5 2TZ
The Village Surgery

Key people:

Investigator:

  • Dr Linda Thompson

Address:

Dudley Lane
Cramlington
Northumberland
NE23 6US
Waterloo Medical Centre

Key people:

Investigator:

  • Dr John Calvert

Address:

178 Waterloo Road
Blackpool
FY34 3AD
Well Close Medical Group

Key people:

Investigator:

  • Dr Stephen Doherty

Address:

Well Close Square
Berwick-upon-Tweed
TD15 1LL
White Medical Group - coming soon

Key people:

Investigator:

  • Dr Richard Holdsworth

Address:

Ponteland Primary Care Centre
Meadowfield
Ponteland
Newcastle upon Tyne
NE20 9SD
Whitefield Health Care

Key people:

Investigator:

  • Dr Catja Schmitgen

Address:

Yarnspinners Health Care Centre
Yarnspinners Wharf
Carr road
Nelson
BB9 7SR
Widdrington Surgery - coming soon

Key people:

Investigator:

  • Dr Yvonne Lees

Address:

Grange Road
Morpeth
NE61 5LX
NHS Fife

Key people:

Investigator:

  • Dr Devesh Dhasmana

Address:

Victoria Hospital
Hayfield Road
Kirkcaldy
Fife
KY2 5AH
Shifa Surgery

Key people:

Investigator:

  • Dr Tanveer Ahmed

Address:

Bangor Street Health Centre
Blackburn
Lancashire
BB1 6DY
Richmond Medical

Key people:

Investigator:

  • Dr Catja Schmitgen

Address:

Acorn Primary Health Care Centre
421 Blackburn Road
Accrington
Lancashire
BB5 1RT
Ninewells Hospital

Key people:

Investigator:

  • Dr Philip Short

Address:

Ninewells Hospital
James Arrott Drive,
Dundee
DD2 1SY
Broadway Medical Centre

Key people:

Investigator:

  • Dr Moazzam Chaudhary

Address:

164 Great N Rd
Newcastle upon Tyne
NE3 5JP
Benfield Park - coming soon

Key people:

Investigator:

  • Dr Paul Netts

Address:

Healthcare & Diagnostic Centre
Benfield Road
Newcastle upon Tyne
NE6 4QD
Discovery Practice

Key people:

Investigator:

  • Dr Seema Singh

Address:

The Health Centre
20 Cleveland Square
Middlesborough
TS1 2NX
Brunel Medical Practice

Key people:

Investigator:

  • Dr Richard Veale

Address:

Brunel Medical Practice
St Albans Road
Torquay
TQ1 3SL
Bovey Tracey & Chudleigh Practice

Key people:

Investigator:

  • Dr Danny Thomas

Address:

Riverside Surgery
Le Molay-Littry Way
Bovey Tracey
Devon
TQ13 9QP
Albany Surgery - coming soon

Key people:

Investigator:

  • Dr Jocelyn Glenton

Address:

Grace House
Scott Close
Newton Abbot
TG12 1GJ
Barton Surgery - coming soon

Key people:

Investigator:

  • Dr Elizabeth Alborough

Address:

Barton Terrace
Dawlish
EX7 9QH
Bideford Medical Centre - coming soon

Key people:

Investigator:

  • Dr Richard Davies

Address:

Bideford Medical Centre
Abbotsham Road
Bideford
EX39 3AF
Brannam Medical Centre - coming soon

Key people:

Investigator:

  • Dr Melanie Deacon

Address:

Brannam Medical Centre
Kiln Lane
Barnstaple
EX32 8GP
Budleigh Salterton Medical Centre - coming soon

Key people:

Investigator:

  • Dr Karen Heaney

Address:

1 The Lawn
Budleigh
Salterton
EX9 6LS
Channel View Medical Practice

Key people:

Investigator:

  • Dr Catherine Hall

Address:

3 Courtenay Place
Teignmouth
TQ14 8AY
Charlestown Surgery - coming soon

Key people:

Investigator:

  • Dr Yuk Chan

Address:

Signal Cottage
1 Main Road
Charlestown
Dunfermline
KY11 3ED
Chilcote Surgery - coming soon

Key people:

Investigator:

  • Dr Emma Funnell

Address:

Hampton Avenue
Torquay
TQ1 3LA
Church View Surgery - coming soon

Key people:

Investigator:

  • Dr Anna Dias

Address:

30 Holland Rd
Plymouth
PL9 9BN
Coleridge Medical Centre - coming soon

Key people:

Investigator:

  • Dr Nigel De Sousa

Address:

Canaan Way
Ottery Saint Mary
EX11 1EQ
Compass House Medical Centre - coming soon

Key people:

Investigator:

  • Dr Leah Jones

Address:

Compass House Medical Centres
King Street
Brixham
Devon
TQ5 9TF
Cricketfield Surgery - coming soon

Key people:

Investigator:

  • Dr Paul Johnson

Address:

Cricket Field Road
Newton Abbot
TQ12 2AS
Empingham Medical Centre

Key people:

Investigator:

  • Dr Mike Eaves

Address:

Main Street
Empingham
Oakham
LE15 8PR
Eric Moore Partnership - coming soon

Key people:

Investigator:

  • Dr Oria Mariscal

Address:

Eric Moore Partnership Medical Practice
Medi Centre
Tanners Lane
warrington
WA2 7NJ
Forth Valley Royal Hospital - coming soon

Key people:

Investigator:

  • Dr Mark Spears

Address:

Stirling Road
Larbert
FK5 4WR
Glastonbury Surgery - coming soon

Key people:

Investigator:

  • Dr Alastair Corfield

Address:

Feversham Lane
Glastonbury
BA6 9LP
Haldon House Surgery - coming soon

Key people:

Investigator:

  • Dr Charu Bowen

Address:

37-41 Imperial Road
Exmouth
EX8 1DQ
The Heavitree Practice - coming soon

Key people:

Investigator:

  • Dr Andy Barker

Address:

Heavitree Health Centre
South Lawn Terrace
Exeter
EX1 2RX
Honiton Surgery

Key people:

Investigator:

  • Dr Daniel Murphy

Address:

Marlpits Lane
Honiton
EX14 2NY
Ide Lane Surgery - coming soon

Key people:

Investigator:

  • Dr Daniel Webber-Rookes

Address:

25 Ide Lane
Exeter
EX2 8UP
Raigmore Hospital - coming soon

Key people:

Investigator:

  • Dr Beth Sage

Address:

Old Perth Road
Inverness
IV2 3UJ
Kingskerswell & Ipplepen Medical Practice - coming soon

Key people:

Investigator:

  • Dr Richard Sandford

Address:

School Road
Kingskerswell
Newton Abbot
TQ12 5DJ
Kingston Hospital

Key people:

Investigator:

  • Dr Siva Mahendran

Address:

Galsworthy Road
Kingston upon Thames
Surrey
KT2 7QB
Knowle House Surgery - coming soon

Key people:

Investigator:

  • Dr Tim Hall

Address:

4 Meavy Way
Plymouth
PL5 3JB
Lindum Medical Practice - coming soon

Key people:

Investigator:

  • Dr Russell Eldridge

Address:

1 Cabourne Court
Lincoln
LN2 2JP
Mounts Bay Medical - coming soon

Key people:

Investigator:

  • Dr Adam Ellery

Address:

Connor Downs Surgery
Turnpike Road
Connor Downs
TR27 5DT
The Newquay Health Centre

Key people:

Investigator:

  • Dr Nick Jacobsen

Address:

St Thomas Road
Newquay
Cornwall
TR7 1RU
Oak Tree Surgery - coming soon

Key people:

Investigator:

  • Dr Rehan Symonds

Address:

Clemo Road
Liskeard
Cornwall
PL14 3XA
Peel House Medical Centre

Key people:

Investigator:

  • Dr Scott Cooper

Address:

1 Paradise Street
Accrington
BB5 2EJ
Richmond Hill Practice - coming soon

Key people:

Investigator:

  • Dr Jabran Ali

Address:

Colne Health Centre
Craddock Road
Colne
Lancashire
BB8 0JZ
Rolle Medical Partnership - coming soon

Key people:

Investigator:

  • Dr William Willcock

Address:

Claremont Grove
Exmouth
EX8 2JF
Rosedean House Surgery - coming soon

Key people:

Investigator:

  • Dr Penelope Atkinson

Address:

8 Dean St
Liskeard
PL14 4AQ
The South Lawn Medical Practice - coming soon

Key people:

Investigator:

  • Dr Katherine Wood

Address:

Heavitree Heath Centre
South Lawn Terrace
Exeter
EX1 2RX
Swarland Avenue Surgery

Key people:

Investigator:

  • Dr Naeem Iqbal

Address:

2 Swarland Avenue
Benton
Newcastle upon Tyne
NE7 7TD
Teign Estuary Medical Group

Key people:

Investigator:

  • Dr Tamsin Venton

Address:

3 Carlton Place
Teignmouth
TQ14 8AB
Teignmouth Medical Practice - coming soon

Key people:

Investigator:

  • Dr Karen Bates

Address:

2 Den Crescent
Teignmouth
Devon
TQ14 8BG
Torrington Health Centre - coming soon

Key people:

Investigator:

  • Dr David Burton

Address:

New Road
Torrington
Devon
EX38 8EL
Vine Surgery Partnership - coming soon

Key people:

Investigator:

  • Dr Sarah Freeman

Address:

Hindhayes Lane
Street
Somerset
BA16 0ET
Wellbrook Medical Centre - coming soon

Key people:

Investigator:

  • Dr Jonathan Marsden

Address:

Welland Road
Hilton
Derby
DE65 5GZ
West Coker Surgery - coming soon

Key people:

Investigator:

  • Dr Lindsay Smith

Address:

High Street
West Coker
Yeovil
Somerset
BA22 9AH
The Westbank Practice - coming soon

Key people:

Investigator:

  • Dr Nimita Gandhi

Address:

The Limes Surgery
Church Stile
Exminster
Devon
EX6 8DF
York Teaching Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Caroline Everett

Address:

York Hospital
Wigginton Rd,
York
YO31 8HE
The Banks Surgery - coming soon

Key people:

Investigator:

  • Dr Stephen Clay

Address:

9 The Banks
Sileby
Loughborough
Leicestershire
LE12 7RD
The Cottage Surgery - coming soon

Key people:

Investigator:

  • Dr Stephen Clay

Address:

The Cottage Surgery
37 Main Street
Woodhouse Eaves
Leicestershire
LE12 8RY
Danetre Medical Practice - coming soon

Key people:

Investigator:

  • Dr Amy Butler

Address:

Danetre Medical Practice
London Rd
Daventry
NN11 4DY
East Leicester Medical Practice - coming soon

Key people:

Investigator:

  • Dr Azhar Farooqi

Address:

East Leicester Medical Practice
Uppingham Road Health Centre
131 Uppingham Rd
Leicester
LE5 4BP
Hockley Farm Medical Practice - coming soon

Key people:

Investigator:

  • Dr Kamlesh Khunti

Address:

Hockley Farm Medical Practice
Braunstone Health & Social Care Centre
39 Hockley Farm Rd
Leicester
LE3 1HN
Jubilee Medical Group

Key people:

Investigator:

  • Dr Wilson Erijoh

Address:

Cobblers Hall Surgery,
Carer's Way
Newton Aycliffe
DL5 4SE
Forest Medical - coming soon

Key people:

Investigator:

  • Dr Richard Park

Address:

Rosemary Street Health Centre
Mansfield
NG19 6AB
Lakeside Healthcare Group - coming soon

Key people:

Investigator:

  • Dr Amardeep Heer

Address:

Lakeside Surgery
Cottingham Road
Corby
Northants
NN17 2UR
Penryn Surgery

Key people:

Investigator:

  • Dr Jonathan Katz

Address:

Saracen Way
Penryn
Cornwall
TR10 8HX
Riverlyn Medical Centre - coming soon

Key people:

Investigator:

  • Dr Chary Tangri

Address:

Station Road
Bulwell
Nottingham
NG6 9AA
Roundwood Surgery - coming soon

Key people:

Investigator:

  • Dr Primal Johnson

Address:

Roundwood Surgery
Wood Street Surgery
Mansfield
Nottinghamshire
NG18 1QQ
Torkard Hill Medical Centre - coming soon

Key people:

Investigator:

  • Dr Prakash Kachhala

Address:

Torkard Hill Medical Centre
Farleys Lane
Hucknall
Nottingham
NG15 6DY
William Brown Medical Centre - coming soon

Key people:

Investigator:

  • Dr David Anderson

Address:

William Brown Medical Centre
Manor Way
Peterlee
Co Durham
SR8 5TW
Tyntesfield Medical Group - coming soon

Key people:

Investigator:

  • Dr Edward Mann

Address:

Tyntesfield Medical Group
Tower House Medical Centre
Stockway South
Nailsea, Bristol
BS48 2XX
Trowbridge Health Centre - coming soon

Key people:

Investigator:

  • Dr Toby Cookson

Address:

Hammersmith Fields
Trowbridge
Wiltshire
BA14 8L
Southmead Hospital

Key people:

Investigator:

  • Dr James Dodd

Address:

North Bristol NHS Trust
Southmead Road
Bristol
BS10 5NB
Queen Elizabeth The Queen Mother Hospital

Key people:

Investigator:

  • Dr Brett Pereira

Address:

St Peters Road
Margate
Kent
CT9 4AN
William Harvey Hospital

Key people:

Investigator:

  • Dr Brett Pereira

Address:

Kennington Road
Willesborough
Ashford
TN24 0LZ
Coxhoe Medical Practice - coming soon

Key people:

Investigator:

  • Dr Rakesh Bhati

Address:

Lansdowne Road
Coxhoe
Durham
DH6 4DH
Willows Medical Centre - coming soon

Key people:

Investigator:

  • Dr Mohammed Roshan

Address:

Willows Medical Centre
184 Coleman Road
Leicester
LE5 4LJ
Royal Surrey County Hospital - coming soon

Key people:

Investigator:

  • Dr Mohamad Ghanem Aldik

Address:

Royal Surrey County Hospital
Egerton Rd
Guildford
GU2 7XX
Royal Liverpool University Hospital

Key people:

Investigator:

  • Dr Hassan Burhan

Address:

Royal Liverpool University Hospital
Prescot St
Liverpool
L7 8XP
Royal Albert Edward Infirmary

Key people:

Investigator:

  • Dr Imran Aziz

Address:

Respiratory Medicine
Royal Albert Edward Infirmary
Wigan Lane
Wigan
WN1 2NN
Layton Medical Centre

Key people:

Investigator:

  • Dr Rebecca Clark

Address:

Layton Medcial Centre
200 Kingscote Drive
Blackpool
Lancashire
FY3 7EN
Rothwell & Desborough Healthcare Group - coming soon

Key people:

Investigator:

  • Dr Karim Khan

Address:

Rothwell Medical Centre
109 Desborough Road
Rothwell
NN14 6JQ
Tamar Valley Health

Key people:

Investigator:

  • Dr David Harris

Address:

Callington Health Centre
Haye Road
Callington
Cornwall
PL14 7AW
Port Isaac Surgery - coming soon

Key people:

Investigator:

  • Dr Nick Hearle

Address:

Port Isaac Surgery
Hillston Close
Port Isaac
Cornwall
PL29 3TR
Park Avenue Medical Centre - coming soon

Key people:

Investigator:

  • Dr Michael Ravest

Address:

166-168 Park Avenue North
Northampton
Northamptonshire
NN3 2HZ
Burnley Wood Medical Centre

Key people:

Investigator:

  • Dr Pauline Patrick

Address:

Burnley Wood Medical Centre
50 Parliament Street
Burnley
BB11 3HR
Brownlow Health - coming soon

Key people:

Investigator:

  • Dr Diane Exley

Address:

70 Pembroke Place
Liverpool
L69 3GF
Blackhall and Peterlee Practice

Key people:

Investigator:

  • Dr Savitri Laloo

Address:

Blackhall Community Health Centre
Hesleden Rd
Blackhall
TS27 4LQ
Claremont Medical Practice

Key people:

Investigator:

  • Dr Lisa Gibbons

Address:

Exmouth Health Centre
Claremont Grove
Exmouth
EX8 2JF
Haltwhistle Medical Group

Key people:

Investigator:

  • Dr Sarah Davies

Address:

Haltwhistle Health Centre
Greencroft Ave
Haltwhistle
NE49 9AP
Priory Gardens Surgery - coming soon

Key people:

Investigator:

  • Dr Nasir Hannan

Address:

The Health Centre
Church Street
Dunstable
LU6 3SU
The Haven Surgery

Key people:

Investigator:

  • Dr Rina Miah

Address:

The Haven
Burnhope
Co Durham
DH7 0BD
Teams Medical Practice - coming soon

Key people:

Investigator:

  • Dr Paul Cassidy

Address:

Watson Street
Gateshead
Tyne & Wear
NE8 2PQ
54.95503
Temple Sowerby Medical Practice - coming soon

Key people:

Investigator:

  • Dr Stacey Fisher

Address:

Linden Park
Temple Sowerby
Penrith
Cumbria
CA10 1RW
Prudhoe Medical Group

Key people:

Investigator:

  • Dr Helen Thornton

Address:

Kepwell Bank Top
Prudhoe
NE42 5PW
Heswall and Pensby Group Practice - coming soon

Key people:

Investigator:

  • Dr Stephen Forster

Address:

270 Telegraph Road
Heswall
CH60 7SG
Queens Road Surgery

Key people:

Investigator:

  • Dr Graham David

Address:

Queens Road Surgery
83 Queens Road
Blackhill
Consett, Co Durham
DH8 0BW
Hall Street Medical Centre - coming soon

Key people:

Investigator:

  • Dr David Reade

Address:

Hall Street Medical Centre
28-30 Hall Street
St Helens
Merseyside
WA10 1DW
The Glebe Practice - coming soon

Key people:

Investigator:

  • Dr Catherine Ash

Address:

The Glebe Practice Saxilby
85 Sykes Lane
Saxilby
Lincoln
LN1 2NU
Kiltearn Medical Centre - coming soon

Key people:

Investigator:

  • Dr Carolyn Paul

Address:

Church View Primary Care centre
Beam Street
Nantwich
CW5 5NX
Ashfield Primary Care Centre - coming soon

Key people:

Investigator:

  • Dr Neil Paul

Address:

19 Middlewich Road
Sandbach
CW 11 1EQ
The Spital Surgery - coming soon

Key people:

Investigator:

  • Dr Athanasios Simopoulos

Address:

1-2 Lancelyn Court Precinct
Spital Road
Bebington
Wirral
CH63 9JP
Pinfold Medical Practice - coming soon

Key people:

Investigator:

  • Dr Ian Brockhurst

Address:

The Health Centre
Pinfold Gate
Loughborough
Leicestershire
LE11 1DQ
Minchinhampton Surgery - coming soon

Key people:

Investigator:

  • Dr Beard John

Address:

The Surgery
Bell Lane
Minchinhampton
Gloucestershire
GL6 9JF
Whiteladies Medical Group - coming soon

Key people:

Investigator:

  • Dr Stephen Garnier

Address:

Whiteladies Health Centre
Whatley Road
Bristol
Avon
BS8 2PU
Mendip Vale Medical Practice - coming soon

Key people:

Investigator:

  • Dr Richard Reed

Address:

Pudding Pie Lane
Langford
Bristol
BS40 5EL
Cadbury Heath Healthcare - coming soon

Key people:

Investigator:

  • Dr Lucy Pocock

Address:

Cadbury Heath Healthcare
Parkwall Road
Cadbury Heath
Bristol
BS30 8HS
Nightingale Valley Practice - coming soon

Key people:

Investigator:

  • Dr Katherine Alsop

Address:

Brooklea Health Centre
Wick Road
Brislington
BS4 4HU
Portishead Medical Group - coming soon

Key people:

Investigator:

  • Dr Emily Lake

Address:

Victoria Square
Portishead
Bristol
BS20 6AQ
St Augustine's Medical Practice - coming soon

Key people:

Investigator:

  • Dr Edward Fletcher

Address:

The Chocolate Factory
Block C
Via Traversus
Keynsham
BS31 2GN
Close Farm Surgery - coming soon

Key people:

Investigator:

  • Dr Ash Singh

Address:

47 Victoria Road
North Common
Bristol
BS30 5JZ
Mann Cottage Surgery - coming soon

Key people:

Investigator:

  • Dr Cathy Bobrow

Address:

Four Shires Medical Centre
Stow Road
Moreton-in-Marsh
Gloucestershire
GL56 0DS
Stow Surgery - coming soon

Key people:

Investigator:

  • Dr Paul Sherringham

Address:

Well Lane
Stow-on-the-Wold
Gloucestershire
GL54 1EQ
Phoenix Health Centre - coming soon

Key people:

Investigator:

  • Dr Naomi Vernon

Address:

9 Chesterton Lane
Circenester
Gloucestershire
GL7 1XG
The Lennard Surgery - coming soon

Key people:

Investigator:

  • Dr Hugh Davies

Address:

1 Lewis Road
Bedminster Down
Bristol
BS13 7JD

Study news

Recruitment

267/1576

Trial sites

Latest addition to sites:

Queens Road Surgery
Prudhoe Medical Group
The Haven Surgery
Haltwhistle Medical Group

Key facts about the study and documents

What is this study about?

This research study is trying to find out if the beta-blocker bisoprolol reduces the number of COPD flare ups (also known as exacerbations). Beta-blockers have been used to treat heart conditions for over 30 years and is safe to use in COPD. There is some evidence that people who have COPD and who take beta-blockers are less likely to have flare-ups. In our study, we want to investigate whether people with COPD who are started on bisoprolol, are less likely to have flare ups.


What will happen to me if I take part?
1. To find out if bisoprolol reduces the number of COPD flare ups we are comparing the effect of bisoprolol against the effect of a placebo ‘dummy treatment’, which looks like the genuine medicine but contains no active ingredient.
2. Each person in the study is put into a group selected randomly by a computer (like tossing a coin). Half of the 1574 people will take bisoprolol and half will take the placebo for a year. To make sure that the true effects of bisoprolol are being studied neither you nor your doctor will know which treatment group you are in (although, if your doctor needs to find out he/she can do so).

What would I have to do?
1. Come to study appointments. We can help with travel expenses. At these appointments we will ask you to do some blowing tests and have an ECG to check your heart’s rythm, measure your height, weight, pulse rate and blood pressure, and tell us about your COPD and any flare-ups you have had.
2. Take the study tablets for a year and make a note of any flare ups of your COPD and how they are treated by your GP. Supplies of study tablets will be sent by courier to your home address.
3. Continue taking all of your normal medicines. If you need to go to your GP for treatment you should go, any flare ups of your COPD can be treated as they normally would.

You can read out more about the study in the patient information leaflet below or ask us to send you a copy in the post. You can also contact us with any questions you have about the study.

You can find out more information about BICS here:

Download documents:

Key contacts

Click on cards to find out more

Key questions & answers

Click on questions to find out more

I’m taking part in the study – how do I contact the local study team?

You can click on the links above to get contact information. Alternatively, you can contact the study office (telephone 01224 438178 or email bics@abdn.ac.uk) and we will put you in touch with your local study team.

Organisation

This project was funded by the National Institute for Health Research Health Technology Assessment (HTA) programme (reference 15/130/20) and is run by the University of Aberdeen, in conjunction NHS Grampian.
The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.

General Data Protection Regulation (GDPR)

Participant Information

University of Aberdeen/NHS Grampian is the sponsor for this study based in the United Kingdom. We will be using information from you and your medical records in order to undertake this study and will act as the data controller for this study. This means that we are responsible for looking after your information and using it properly. University of Aberdeen/NHS Grampian will keep identifiable information about you at least 15 years after the study has finished.

Your rights to access, change or move your information are limited, as we need to manage your information in specific ways in order for the research to be reliable and accurate. If you withdraw from the study, we will keep the information about you that we have already obtained. To safeguard your rights, we will use the minimum personally-identifiable information possible.

You can find out more about how we use your information https://www.abdn.ac.uk/about/privacy/