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WELCOME TO THE PANDOS STUDY

Pain AND Opioids after Surgery (the PANDOS study).

What is PANDOS?

The aim of this study is to document the perioperative (around the time of surgery) opioid use in the UK and countries in Europe and to describe its association with surgical complications, persistent pain and quality of life.

In an international, prospective, observational cohort study, data about the perioperative pain management will be collected in all eligible hospitalised adult patients who undergo surgery in a designated “study week” in as many hospitals as possible in the UK and Europe. Baseline data will be collected, and participants followed up at one week, and at three and twelve months post-operatively.

The primary outcome will be opioid use at three months after surgery.

Secondary outcomes will include opioid use during the preoperative month (preoperative use), during surgery and up to one week after surgery (or discharge, whichever is earlier), and up to the end of the postoperative year. Additional secondary outcomes are the incidence of preoperative pain, persistent pain with/without the presence of neuropathic components, quality of life and surgical complications.

The potential association between opioid use and pain outcomes will be investigated. This study could help to develop strategies to improve quality of care, through pain management, for patients undergoing surgery.
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Who will be taking part?

Hospitalised adult patients (18 years and older) undergoing (or scheduled to undergo) any inpatient surgery (elective or emergency) during the designated study week (at the hospital) where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic).

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If you are interested in taking part, or have any questions

CONTACT US

Where can I take part?

Aberdeen

Key people:

Investigator:

  • Prof Patrice Forget

Address:

Aberdeen Royal Infirmary
Foresterhill
Aberdeen
AB25 2ZN
Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Anthony Short

Address:

Wrightington, Wigan and Leigh Teaching Hospitals N
Wigan Lane,
Wigan
WN1 2NN
NHS Fife

Key people:

Investigator:

  • Fiona Bull

Address:

NHS Fife
Hayfield House
Hayfield Road
Kirkcaldy
KY2 5AH
Barnsley Hospital NHS Foundation Trust

Key people:

Investigator:

  • Nigel Bullock

Address:

Barnsley Hospital NHS Foundation Trust
Gawber Road
Barnsley
South Yorkshire
S75 2EP
UNIVERSITY COLLEGE LONDON HOSPITALS NHS FOUNDATION TRUST

Key people:

Investigator:

  • Alan Fayaz

Address:

UNIVERSITY COLLEGE LONDON NHS FOUNDATION TRUST
235 Euston Road
London
NW1 2BU
Guy’s and St Thomas' NHS Foundation Trust

Key people:

Investigator:

  • Prof Kariem El-Boghdadly

Address:

Guy’s and St Thomas' NHS Foundation Trust
249 Westminster Bridge Road
London
SE1 7EH
NHS Highland, Inverness

Key people:

Investigator:

  • Dr Dev Srivastava

Address:

NHS Highland
Assynt House, Beechwood Park
Inverness
IV2 3BW
Northern Care Alliance NHS Foundation Trust - The Royal Oldham Hospital

Key people:

Investigator:

  • Vivek Sinha

Address:

The Royal Oldham Hospital
Rochdale Road
Oldham
OL1 2JH
Northern Care Alliance NHS Foundation Trust - Fairfield General Hospital, Bury

Key people:

Investigator:

  • Pamela Bradley

Address:

Fairfield General Hospital
Rochdale Old Road
Bury
BL9 7TD
Guy's & St Thomas' NHS Foundation Trust

Key people:

Investigator:

  • Dr Nandor Marczin

Address:

Harefield Hospital
THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST - Royal Victoria-

Key people:

Investigator:

  • Alison Blackburn

Address:

Newcastle - Royal Victoria Infirmary
Queen Victoria Road
Newcastle Upon Tyne
NE1 4LP
NHS Tayside, Dundee

Key people:

Investigator:

  • Dr Amy Sadler

Address:

NHS Tayside
Ninewells Hospital & Medical School
Dundee
DD1 9SY
NHS Highland

Key people:

Investigator:

  • Dr Dev Srivastava

Address:

Nottingham University Hospitals NHS Trust

Key people:

Investigator:

Address:

Nottingham University Hospitals NHS Trust
Derby Road
Nottingham
NG7 2UY
NHS Greater Glasgow & Clyde - Royal Infirmary

Key people:

Investigator:

  • Dr Sonya McKinlay

Address:

Glasgow Royal Infirmary
84 Castle Street
Glasgow
G4 0SF
Hywel Dda Health Board - West Wales General Hospital

Key people:

Investigator:

  • Peter Havalda

Address:

West Wales General Hospital
Dolgwili Road
Carmarthen
SA31 2AF
University Hospital Ayr

Key people:

Investigator:

  • Dr Katrina Dick

Address:

University Hospital Crosshouse
Kilmarnock Road
Crosshouse
KA2 0BE
Musgrove Park Hospital

Key people:

Investigator:

  • Edward Keevil

Address:

Musgrove Park,
Taunton
TA1 5DA
Scarborough Teaching Hospital

Key people:

Investigator:

  • Ben Chandler

Address:

Scarborough Teaching Hospital
Woodlands Drive
Scarborough
YO12 6QL
York Teaching Hospital

Key people:

Investigator:

  • Simon Davies

Address:

York Teaching Hospital
The Old Chapel
Bootham Park
York
YO31 8HE
University Hospitals Coventry & Warwickshire NHS Trust

Key people:

Investigator:

  • Dr Davina Hewitt

Address:

University Hospitals Coventry & Warwickshire
Clifford Bridge Road
Coventry
CV2 2DX
University Hospitals of Derby and Burton NHS Foundation Trust (RTG)

Key people:

Investigator:

  • Dr M Haldar

Address:

University Hospitals of Derby and Burton
Belvedere Road
Burton-On-Trent
DE13 0RB
Royal Papworth Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Andrew Klein

Address:

Papworth Road
Cambridge Biomedical Campus
Cambridge
CB2 OSL
Winchester

Key people:

Investigator:

  • Kathleen Hempenstall

Address:

Royal Hampshire County Hospital
Romsey Road
Winchester
SO22 5DG
Hull University Teaching Hospitals NHS Trust

Key people:

Investigator:

  • Dr Pradipta Bhakta

Address:

Hull University Teaching Hospitals NHS Trust
Hull Royal Infirmary
Anlaby Road
Hull
HU3 2JZ
Salisbury NHS Foundation Trust

Key people:

Investigator:

  • Dr Xantha Holmwood

Address:

Salisbury NHS Foundation Trust
Odstock Road
Salsibury
SP2 8BJ
Sherwood Forest Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Srini Magham

Address:

Sherwood Forest Hospitals NHS Foundation Trust
King's Mill Hospital,
Sutton In Ashfield
NG17 4JL
South Tyneside and Sunderland NHS Foundation Trust

Key people:

Investigator:

  • Iain Ross Dryborough

Address:

South Tyneside and Sunderland NHS Foundation Trust
Harton Lane
South Shields
NE34 0PL
Stockport NHS Foundation Trust - Stepping Hill Hospital

Key people:

Investigator:

  • Dr Hywell Garrad

Address:

Stepping Hill Hospital
Poplar Grove
Hazel Grove
Stockport
SK2 7JE
Betsi Cadwaladr University Health Board, Glan Clwyd Hospital

Key people:

Investigator:

  • Venkat Sundaram

Address:

Betsi Cadwaladr University Health Board
Glan Clwyd Hospital
Rhuddlan Road
Rhyl
LL18 5UJ
Hull University Hospital Trust, Castle Hill Hospital

Key people:

Investigator:

  • Pradipta Bhakta

Address:

Hull University Hospital Trust
astle Hill Hospital
Castle Road
Cottingham
HU16 5JQ
Wycombe, Buckinghamshire

Key people:

Investigator:

  • Thomas Grant

Address:

Wycombe Hospital
Queen Alexandra Road
High Wycombe
HP11 2TT
Royal Glamorgan Hospital, Cwm Taf UHB

Key people:

Investigator:

  • Stuart Jenkins

Address:

Royal Glamorgan Hospital
Rhondda Cynon Taf
Llantrisant
CF72 8XR
Kingston Hospital

Key people:

Investigator:

  • Dr Sarang Puranik

Address:

Kingston Hospital
Galsworthy Road
Kingston Upon Thames
KT2 7QB
Walton Centre, Liverpool

Key people:

Investigator:

  • Miroslava Koleva

Address:

The Walton Centre
Lower Lane
Liverpool
L9 7LJ
Rotherham NHS Foundation Trust

Key people:

Investigator:

  • Prof Anil Hormis

Address:

Rotherham NHS Foundation Trust
Rotherham Hospital
Moorgate Road
Rotherham
S60 2UD
Luton and Dunstable Hospital

Key people:

Investigator:

  • Dr Monica Kuradagi

Address:

Luton and Dunstable Hospital
Lewsey Road
Luton
LU4 0DZ
University Hospital Southampton NHS Trust

Key people:

Investigator:

  • Cathy Price

Address:

University Hospital Southampton NHS Trust
Tremona Road
Southampton
SO16 6YD
Colchester, East Suffolk and North Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Joanna Simpson

Address:

Colchester, East Suffolk and North Essex NHS Trust
Colchester Geneal Hospital
Turner Road
Colchester
CO4 5JL
East Suffolk and North Essex NHS Foundation Trust

Key people:

Investigator:

  • Laura Perry

Address:

East Suffolk and North Essex NHS Foundation Trust
Ipswich Hospital
Heath Road
Ipswich
IP4 5PD
Royal Cornwall Hospital Trust

Key people:

Investigator:

  • Dr Preedy

Address:

Royal Cornwall Hospitals NHS Trust
Cornwall Hospital
Truro
TR1 3LJ
Royal Free London NHS Foundation Trust, Barnet Hospital

Key people:

Investigator:

  • Dr Usamah Kidwai

Address:

Royal Free London NHS Foundation Trust
Barnet Hospital
Wellhouse Lane
Barnet
EN5 3DJ
East Lancashire Hospitals NHS Trust, Royal Blackburn

Key people:

Investigator:

  • Dr Anuradha Kurvey

Address:

East Lancashire Hospitals NHS Trust
Royal Blackburn Teaching Hospital
Haslingden Road
Blackburn
BB2 3HH
East Lancashire Hospitals NHS Trust, Burnley General

Key people:

Investigator:

  • Dr Anuradha Kurvey

Address:

East Lancashire Hospitals NHS Trust
Burnley General Hospital
Casterton Avenue
Burnley
BB10 2PQ
NHS Dumfries and Galloway

Key people:

Investigator:

  • Dr Alasdair Hay

Address:

NHS Dumfries and Galloway
Bankhead Road
Dumfries
DG1 4AP
Mid & South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Alistair Hughes

Address:

Mid & South Essex NHS Foundation Trust
Court Road
Broomfield
Chelmsford
CM1 7ET
University Hospitals Dorset

Key people:

Investigator:

  • Robert Wiltshire

Address:

University Hospitals Dorset, Bournemouth
Gillett Road
Talbot Village
Hillbourne
BH12 5BF
University Hospitals Dorset

Key people:

Investigator:

  • Robert Witshire

Address:

University Hospitals Dorset, Bournemouth
Gillett Road
Talbot Village
Hillbourne
BH12 5BF
West Hertfordshire Teaching Hospitals NHS Trust

Key people:

Investigator:

  • Dr Nidhi Gautam

Address:

West Hertfordshire Teaching Hospitals NHS Trust
Vicarage Road
Watford
Hertfordshire
WD18 0HB
University Hospital Hairmyres, NHS Lanarkshire

Key people:

Investigator:

  • Dr John O'Donoghue

Address:

G75 8RG
Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Mr Tim Wilson

Address:

Doncaster & Bassetlaw Teaching Hospitals NHS Trust
Armthorpe Road
Doncaster
DN2 5LT
Tameside General Hospital

Key people:

Investigator:

  • Dr Ranvir Singh

Address:

Tameside General Hospital
Fountain Street
Ashton-Under-Lyne
OL6 9RW
James Cook University hospital

Key people:

Investigator:

  • Dr Lisa Molus

Address:

The James cook University Hospital
Marton Road
Middlesbrough
TS4 3BW
Kent and Canterbury Hospital

Key people:

Investigator:

  • Dr Muhammad Zubair

Address:

Ethelbert Road,
Canterbury
CT1 3NG
Milton Keynes Hospital

Key people:

Investigator:

  • Dr Venkatraman Hariharan

Address:

Milton Keynes University Hospital
Standing Way
Eaglestone
Milton Keynes
MK6 5LD
The Royal Orthopaedic Hospital NHS Foundation Trust

Key people:

Investigator:

  • Eleanor Keeling

Address:

Bristol Road South
Birmingham
B31 2AP
Queen’s Hospital, Romford, Barking, Havering and Redbridge University Hospitals NHS Trust

Key people:

Investigator:

  • Tatiana Pogreban

Address:

Rom Valley Way
Romford
Greater London
RM7 0AG
King George Hospital, Goodmayes, Barking, Havering and Redbridge University Hospitals NHS Trust

Key people:

Investigator:

  • Tatiana Pogreban

Address:

Barley Lane Goodmayes
Goodmayes
Greater London
IG3 8YB
Chelsea & Westminster Hospital NHS Foundation

Key people:

Investigator:

  • Dr Marcela Vizcaychipi

Address:

Chelsea and Westminster Hospital
369 Fulham Road

London
SW10 9NH
Chelsea & Westminster Hospital NHS Foundation

Key people:

Investigator:

  • Dr Priyakam Chowdhury

Address:

Twickenham Road
Isleworth
TW7 6AF
County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

  • Dr Robert Lyons

Address:

Darlington Memorial Hospital
Hollyhurst Road
Darlington
DL36HX
County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

Address:

DH1 5TW
United Lincolnshire Hospitals Trust

Key people:

Investigator:

  • Dr Teodora Orasanu

Address:

Greetwell Rd
Lincoln
LN2 5QY
United Lincolnshire Hospitals Trust

Key people:

Investigator:

  • Dr Manish Chablani

Address:

PE21 9QS
United Lincolnshire Hospitals Trust

Key people:

Investigator:

  • Dr Teodora Orasanu

Address:

NG31 8DG
Surrey and Sussex Healthcare NHS Trust

Key people:

Investigator:

  • Dr Antony Ratnasingham

Address:

RH1 5RH
Queen's Medical Centre, Nottingham

Key people:

Investigator:

  • Dr James Morris

Address:

NG7 2UH
NHS Greater Glasgow and Clyde

Key people:

Investigator:

  • Dr Robin Williams

Address:

G51 4TF
Whittington Health NHS Trust

Key people:

Investigator:

  • Dr Basil Almahdi

Address:

N19 5NF
Peterborough Hospital

Key people:

Investigator:

  • Dr Amitabh Lahkar

Address:

PE3 9GZ
Northampton General Hospital NHS Trust

Key people:

Investigator:

  • Dr Sadasivan Chinniah

Address:

NN1 5BD
University Hospital Sussex NHS Foundation Trust

Key people:

Investigator:

  • Dr Nicholas Attaway

Address:

BN2 5BE
University Hospital Sussex NHS Foundation Trust

Key people:

Investigator:

  • Dr Nicholas Attaway

Address:

RH16 4EX
North West Anglia NHS Foundation Trust

Key people:

Investigator:

  • Sivaprakash Vaitheeswaran

Address:

PE29 6NT
The Robert Jones And Agnes Hunt Orthopaedic Hospital NHS Trust

Key people:

Investigator:

  • Mel Bloor

Address:

SY10 7AG
Mid and South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Pallavi Marghade

Address:

SS16 5NL
East Kent Hospitals University NHS Foundation Trust

Key people:

Investigator:

  • Dr Sarah Hare

Address:

TN24 0LZ
Mid and South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Bobby Krishnachetty

Address:

SS0 0RY
Liverpool University Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Richard Ramsaran

Address:

L7 8XP
Liverpool University Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Richard Ramsaran

Address:

L14 3LB
University Hospitals of Derby and Burton

Key people:

Investigator:

  • Dr Nagendra Prasad

Address:

DE22 3NE
Royal Surrey County Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Matthew Evans

Address:

GU2 7XX
Cumberland Infirmary

Key people:

Investigator:

  • Dr Geetanjali Verma

Address:

CA2 7HY
West Cumberland Hospital

Key people:

Investigator:

  • Dr Elena Grani

Address:

CA28 8JG
Royal Cornwall Hospital Trust

Key people:

Investigator:

  • Dr Preedy

Address:

TR27 4JA
Cambridge University Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Evan Weeks

Address:

CB2 0QQ
Blackpool Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Andy Yuet Meng Ng

Address:

FY3 8NR
Bart's Health NHS Trust

Key people:

Investigator:

  • Dr Sibtain Anwar

Address:

EC1A 7BE
Serbia

Key people:

Investigator:

  • Dr Jelena Jovicic

Address:

Serbia

Key people:

Investigator:

  • Dr Nada Pejcic

Address:

Serbia

Key people:

Investigator:

  • Dr Milijana Miljkovic

Address:

Serbia

Key people:

Investigator:

  • Dr Suzana Bojic

Address:

Serbia

Key people:

Investigator:

  • Dr Marija Milenkovic

Address:

Serbia

Key people:

Investigator:

  • Dr Dragana Unic-Stojanovic

Address:

Serbia

Key people:

Investigator:

  • Dr Svetlana Sreckovic

Address:

Serbia

Key people:

Investigator:

  • Dr Emilija Raspopovic

Address:

Serbia

Key people:

Investigator:

  • Dr Dragana Radovanovic

Address:

Oncology Institute of Vojvodina, Sremska Kamenica
Serbia

Key people:

Investigator:

  • Dr Ivan Petrovic

Address:

Serbia

Key people:

Investigator:

  • Dr Jasna Gacic

Address:

Serbia

Key people:

Investigator:

  • Dr Marina Stojanovic

Address:

Macedonia

Key people:

Investigator:

  • Dr Aleksandra Gavrilovska

Address:

Macedonia

Key people:

Investigator:

  • Dr Nikola Brzanov

Address:

Macedonia

Key people:

Investigator:

  • Dr Marija Srceva

Address:

Macedonia

Key people:

Investigator:

  • Dr Sofija Ohanesjan

Address:

Macedonia

Key people:

Investigator:

  • Dr Marjana Burmuzoska

Address:

Spain

Key people:

Investigator:

  • Dr Angel Becerra-Bolanos

Address:

Macedonia

Key people:

Investigator:

  • Dr Nadica Mehmedovic

Address:

Macedonia

Key people:

Investigator:

  • Dr Dona Adramanova

Address:

Serbia

Key people:

Investigator:

  • Dr Ivan Palibrk

Address:

Spain

Key people:

Investigator:

  • Dr Astrid Batalla

Address:

Spain

Key people:

Investigator:

  • Dr Enrique Alday Muñoz

Address:

Spain

Key people:

Investigator:

  • Dr Aizpea Bernas Albeniz

Address:

Macedonia

Key people:

Investigator:

  • Dr Laureta Mena

Address:

Macedonia

Key people:

Investigator:

  • Prof Atans Sivevski

Address:

Ireland

Key people:

Investigator:

  • Dr Cormac Mullins

Address:

Ireland

Key people:

Investigator:

  • Dr Andrew Purcell

Address:

Serbia

Key people:

Investigator:

  • Dr Mirka Lukic-Sarkanovic

Address:

Ireland

Key people:

Investigator:

  • Dr Orla Kerr

Address:

Spain

Key people:

Investigator:

  • Dr Laura Fernández Téllez

Address:

Turkey

Key people:

Investigator:

  • Dr Berna Caliskan

Address:

Spain

Key people:

Investigator:

  • Dr FRANCISCO JAVIER BOCOS

Address:

Turkey

Key people:

Investigator:

  • Sevtap Hekimoglu Sahin

Address:

Ireland

Key people:

Investigator:

  • Dr Amy Donnelly

Address:

Study news

Recruitment

4896/12,000

Trial sites

Latest addition to sites:

Ireland
Turkey
Spain
Turkey

Key facts about the study and documents

What is this study about?

The main aim of the PANDOS study is to document the use of opioids around the time of surgery (and it’s safety) in Europe. It also aims to look at the association of opioid use around the time of surgery with surgical complications, persistent pain and quality of life.

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You can find out more information about PANDOS here:

Download documents:

PANDOS PIL (v3)
PIL Version 5 3 January 2024 (Version 5 3 January 2024)

Key contacts

Click on cards to find out more

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Key questions & answers

Click on questions to find out more

Organisation

Funding acknowledgement

The study is funded by the European Society of Anaesthesiology and Intensive Care. The views expressed are those of the author(s).