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WELCOME TO THE PANDOS STUDY

Pain AND Opioids after Surgery (the PANDOS study).

What is PANDOS?

The aim of this study is to document the perioperative (around the time of surgery) opioid use in the UK and countries in Europe and to describe its association with surgical complications, persistent pain and quality of life.

In an international, prospective, observational cohort study, data about the perioperative pain management will be collected in all eligible hospitalised adult patients who undergo surgery in a designated “study week” in as many hospitals as possible in the UK and Europe. Baseline data will be collected, and participants followed up at one week, and at three and twelve months post-operatively.

The primary outcome will be opioid use at three months after surgery.

Secondary outcomes will include opioid use during the preoperative month (preoperative use), during surgery and up to one week after surgery (or discharge, whichever is earlier), and up to the end of the postoperative year. Additional secondary outcomes are the incidence of preoperative pain, persistent pain with/without the presence of neuropathic components, quality of life and surgical complications.

The potential association between opioid use and pain outcomes will be investigated. This study could help to develop strategies to improve quality of care, through pain management, for patients undergoing surgery.
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Who will be taking part?

Hospitalised adult patients (18 years and older) undergoing (or scheduled to undergo) any inpatient surgery (elective or emergency) during the designated study week (at the hospital) where an anaesthetist is involved (general anaesthetic, sedation, local anaesthetic).

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If you are interested in taking part, or have any questions

CONTACT US

Where can I take part?

Aberdeen

Key people:

Investigator:

  • Prof Patrice Forget

Address:

Aberdeen Royal Infirmary
Foresterhill
Aberdeen
AB25 2ZN
Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Dr Anthony Short

Address:

Wrightington, Wigan and Leigh Teaching Hospitals N
Wigan Lane,
Wigan
WN1 2NN
NHS Fife

Key people:

Investigator:

  • Fiona Bull

Address:

NHS Fife
Hayfield House
Hayfield Road
Kirkcaldy
KY2 5AH
Barnsley Hospital NHS Foundation Trust

Key people:

Investigator:

  • Nigel Bullock

Address:

Barnsley Hospital NHS Foundation Trust
Gawber Road
Barnsley
South Yorkshire
S75 2EP
UNIVERSITY COLLEGE LONDON HOSPITALS NHS FOUNDATION TRUST

Key people:

Investigator:

  • Alan Fayaz

Address:

UNIVERSITY COLLEGE LONDON NHS FOUNDATION TRUST
235 Euston Road
London
NW1 2BU
Northern Care Alliance NHS Foundation Trust - The Royal Oldham Hospital

Key people:

Investigator:

  • Vivek Sinha

Address:

The Royal Oldham Hospital
Rochdale Road
Oldham
OL1 2JH
Northern Care Alliance NHS Foundation Trust - Fairfield General Hospital, Bury

Key people:

Investigator:

  • Pamela Bradley

Address:

Fairfield General Hospital
Rochdale Old Road
Bury
BL9 7TD
THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST - Freeman Hospital

Key people:

Investigator:

  • Alison Blackburn

Address:

Freeman Royal Hospital
Freeman Road
Newcastle
Newcastle Upon Tyne
NE7 7DN
THE NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST - Royal Victoria-

Key people:

Investigator:

  • Alison Blackburn

Address:

Newcastle - Royal Victoria Infirmary
Queen Victoria Road
Newcastle Upon Tyne
NE1 4LP
NHS Tayside, Dundee

Key people:

Investigator:

  • Dr Amy Sadler

Address:

NHS Tayside
Ninewells Hospital & Medical School
Dundee
DD1 9SY
Nottingham University Hospitals NHS Trust

Key people:

Investigator:

Address:

Nottingham University Hospitals NHS Trust
Derby Road
Nottingham
NG7 2UY
NHS Greater Glasgow & Clyde - Royal Infirmary

Key people:

Investigator:

  • Dr Sonya McKinlay

Address:

Glasgow Royal Infirmary
84 Castle Street
Glasgow
G4 0SF
Hywel Dda Health Board - West Wales General Hospital

Key people:

Investigator:

  • Peter Havalda

Address:

West Wales General Hospital
Dolgwili Road
Carmarthen
SA31 2AF
University Hospital Ayr

Key people:

Investigator:

  • Dr Katrina Dick

Address:

University Hospital Crosshouse
Kilmarnock Road
Crosshouse
KA2 0BE
Musgrove Park Hospital

Key people:

Investigator:

  • Edward Keevil

Address:

Musgrove Park,
Taunton
TA1 5DA
Scarborough Teaching Hospital

Key people:

Investigator:

  • Ben Chandler

Address:

Scarborough Teaching Hospital
Woodlands Drive
Scarborough
YO12 6QL
York Teaching Hospital

Key people:

Investigator:

  • Simon Davies

Address:

York Teaching Hospital
The Old Chapel
Bootham Park
York
YO31 8HE
University Hospitals of Derby and Burton NHS Foundation Trust (RTG)

Key people:

Investigator:

  • Dr M Haldar

Address:

University Hospitals of Derby and Burton
Belvedere Road
Burton-On-Trent
DE13 0RB
Royal Papworth Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Andrew Klein

Address:

Papworth Road
Cambridge Biomedical Campus
Cambridge
CB2 OAY
Winchester

Key people:

Investigator:

  • Kathleen Hempenstall

Address:

Royal Hampshire County Hospital
Romsey Road
Winchester
SO22 5DG
Hull University Teaching Hospitals NHS Trust

Key people:

Investigator:

  • Dr Pradipta Bhakta

Address:

Hull University Teaching Hospitals NHS Trust
Hull Royal Infirmary
Anlaby Road
Hull
HU3 2JZ
Salisbury NHS Foundation Trust

Key people:

Investigator:

  • Dr Xantha Holmwood

Address:

Salisbury NHS Foundation Trust
Odstock Road
Salsibury
SP2 8BJ
Sherwood Forest Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Srini Magham

Address:

Sherwood Forest Hospitals NHS Foundation Trust
King's Mill Hospital,
Sutton In Ashfield
NG17 4JL
South Tyneside and Sunderland NHS Foundation Trust

Key people:

Investigator:

  • Iain Ross Dryborough

Address:

South Tyneside and Sunderland NHS Foundation Trust
Harton Lane
South Shields
NE34 0PL
Betsi Cadwaladr University Health Board, Glan Clwyd Hospital

Key people:

Investigator:

  • Venkat Sundaram

Address:

Betsi Cadwaladr University Health Board
Glan Clwyd Hospital
Rhuddlan Road
Rhyl
LL18 5UJ
Hull University Hospital Trust, Castle Hill Hospital

Key people:

Investigator:

  • Pradipta Bhakta

Address:

Hull University Hospital Trust
astle Hill Hospital
Castle Road
Cottingham
HU16 5JQ
Wycombe, Buckinghamshire

Key people:

Investigator:

  • Thomas Grant

Address:

Wycombe Hospital
Queen Alexandra Road
High Wycombe
HP11 2TT
Royal Glamorgan Hospital, Cwm Taf UHB

Key people:

Investigator:

  • Stuart Jenkins

Address:

Royal Glamorgan Hospital
Rhondda Cynon Taf
Llantrisant
CF72 8XR
Kingston Hospital

Key people:

Investigator:

  • Dr Sarang Puranik

Address:

Walton Centre, Liverpool

Key people:

Investigator:

  • Miroslava Koleva

Address:

The Walton Centre
Lower Lane
Liverpool
L9 7LJ
Rotherham NHS Foundation Trust

Key people:

Investigator:

  • Prof Anil Hormis

Address:

Rotherham NHS Foundation Trust
Rotherham Hospital
Moorgate Road
Rotherham
S60 2UD
University Hospital Southampton NHS Trust

Key people:

Investigator:

  • Cathy Price

Address:

University Hospital Southampton NHS Trust
Tremona Road
Southampton
SO16 6YD
Colchester, East Suffolk and North Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Mohamed Ramali

Address:

Colchester, East Suffolk and North Essex NHS Trust
Colchester Geneal Hospital
Turner Road
Colchester
CO4 5JL
East Suffolk and North Essex NHS Foundation Trust

Key people:

Investigator:

  • Laura Perry

Address:

East Suffolk and North Essex NHS Foundation Trust
Ipswich Hospital
Heath Road
Ipswich
IP4 5PD
Royal Cornwall Hospital Trust

Key people:

Investigator:

  • Dr Preedy

Address:

Royal Cornwall Hospitals NHS Trust
Cornwall Hospital
Truro
TR1 3LJ
Royal Free London NHS Foundation Trust, Barnet Hospital

Key people:

Investigator:

  • Dr Usamah Kidwai

Address:

Royal Free London NHS Foundation Trust
Barnet Hospital
Wellhouse Lane
Barnet
EN5 3DJ
Mid & South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Alistair Hughes

Address:

Mid & South Essex NHS Foundation Trust
Court Road
Broomfield
Chelmsford
CM1 7ET
University Hospitals Dorset

Key people:

Investigator:

  • Robert Wiltshire

Address:

University Hospitals Dorset, Bournemouth
Gillett Road
Talbot Village
Hillbourne
BH12 5BF
University Hospitals Dorset

Key people:

Investigator:

  • Robert Witshire

Address:

University Hospitals Dorset, Bournemouth
Gillett Road
Talbot Village
Hillbourne
BH12 5BF
West Hertfordshire Teaching Hospitals NHS Trust

Key people:

Investigator:

  • Dr Nidhi Gautam

Address:

West Hertfordshire Teaching Hospitals NHS Trust
Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust

Key people:

Investigator:

  • Mr Tim Wilson

Address:

Doncaster & Bassetlaw Teaching Hospitals NHS Trust
Armthorpe Road
Doncaster
DN2 5LT
Tameside General Hospital

Key people:

Investigator:

  • Dr Ranvir Singh

Address:

Tameside General Hospital
Fountain Street
Ashton-Under-Lyne
OL6 9RW
James Cook University hospital

Key people:

Investigator:

  • Dr Lisa Molus

Address:

The James cook University Hospital
Marton Road
Middlesbrough
TS4 3BW
Kent and Canterbury Hospital

Key people:

Investigator:

  • Dr Muhammad Zubair

Address:

Ethelbert Road,
Canterbury
CT1 3NG
Milton Keynes Hospital

Key people:

Investigator:

  • Dr Venkatraman Hariharan

Address:

Milton Keynes University Hospital
Standing Way
Eaglestone
Milton Keynes
MK6 5LD
The Royal Orthopaedic Hospital NHS Foundation Trust

Key people:

Investigator:

  • Eleanor Keeling

Address:

Bristol Road South
Birmingham
B31 2AP
Queen’s Hospital, Romford, Barking, Havering and Redbridge University Hospitals NHS Trust

Key people:

Investigator:

  • Tatiana Pogreban

Address:

Rom Valley Way
Romford
Greater London
RM7 0AG
King George Hospital, Goodmayes, Barking, Havering and Redbridge University Hospitals NHS Trust

Key people:

Investigator:

  • Tatiana Pogreban

Address:

Barley Lane Goodmayes
Goodmayes
Greater London
IG3 8YB
Chelsea & Westminster Hospital NHS Foundation

Key people:

Investigator:

  • Dr Marcela Vizcaychipi

Address:

Chelsea & Westminster Hospital NHS Foundation

Key people:

Investigator:

  • Dr Priyakam Chowdhury

Address:

County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

  • Dr Robert Lyons

Address:

Darlington Memorial Hospital
Hollyhurst Road
Darlington
DL36HX
County Durham and Darlington NHS Foundation Trust

Key people:

Investigator:

Address:

Surrey and Sussex Healthcare NHS Trust

Key people:

Investigator:

  • Dr Antony Ratnasingham

Address:

NHS Greater Glasgow and Clyde

Key people:

Investigator:

  • Dr Robin Williams

Address:

Whittington Health NHS Trust

Key people:

Investigator:

  • Dr Basil Almahdi

Address:

Peterborough Hospital

Key people:

Investigator:

  • Dr Amitabh Lahkar

Address:

North West Anglia NHS Foundation Trust

Key people:

Investigator:

  • Sivaprakash Vaitheeswaran

Address:

Mid and South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Pallavi Marghade

Address:

Mid and South Essex NHS Foundation Trust

Key people:

Investigator:

  • Dr Bobby Krishnachetty

Address:

Liverpool University Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Richard Ramsaran

Address:

Liverpool University Hospital NHS Foundation Trust

Key people:

Investigator:

  • Dr Richard Ramsaran

Address:

Royal Cornwall Hospital Trust

Key people:

Investigator:

  • Dr Preedy

Address:

Study news

Recruitment

2271/12,000

Trial sites

Latest addition to sites:

Royal Cornwall Hospital Trust
Liverpool University Hospital NHS Foundation Trust
Liverpool University Hospital NHS Foundation Trust
Mid and South Essex NHS Foundation Trust

Key facts about the study and documents

What is this study about?

The main aim of the PANDOS study is to document the use of opioids around the time of surgery (and it’s safety) in Europe. It also aims to look at the association of opioid use around the time of surgery with surgical complications, persistent pain and quality of life.

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You can find out more information about PANDOS here:

Download documents:

PANDOS PIL (v3)
PIL Version 5 3 January 2024 (Version 5 3 January 2024)

Key contacts

Click on cards to find out more

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Key questions & answers

Click on questions to find out more

Organisation

Funding acknowledgement

The study is funded by the European Society of Anaesthesiology and Intensive Care. The views expressed are those of the author(s).