Journal Ref. |
Barraclough M: Control of moderately raised blood pressure. Report of a co-operative randomized controlled trial. Br Med J 1973, 3:434-436. |
Intervention |
Drug - bendrofluazide with potassium supplement, methyldopa, or debrisoquine |
Number of sites |
2 |
Countries involved |
UK |
Sample size |
58 |
Type of statistical analyses |
|
Risk of bias |
Overall: High Risk
details
Random sequence generation:
Low Risk
Allocation concealment:
Unclear
Blinding of participants, personal and outcome assessors:
High Risk
Incomplete outcome data:
High Risk
Selective outcome reporting:
Low Risk
Other sources of bias:
Low Risk
|
Duration of trial |
July 1967-December 1970 |
Primary outcome |
Cardiovascular incidents |