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WELCOME TO REFLECT

A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs

COVID-19 update

In response to COVID-19, the study team are working from home. We are continuing to keep in touch with participants in the study. It may be that we are in touch with you by a different method than usual (for example we may telephone you to complete questionnaires, rather than send them by post). If you have any questions about the study, please get in touch on 01224 438134 (and leave a message) or email. reflect@abdn.ac.uk.

If you are a patient and require medical attention or advice, please contact your GP or NHS-111/NHS-24 (by dialling 111).

You can also find information about COVID-19 from the NHS websites in England ,Scotland, Wales and Northern Ireland.

There is also information about COVID-19 on the UK government website.

What is REFLECT?

Recent research has found that many more people are keeping their own teeth for longer. Although this is a good thing it also means that when people begin to suffer with decay, the treatments required are more complex and expensive and may be very costly. There is a need to help people keep their own teeth free from decay as long as possible.

Since the 1970’s fluoride toothpaste has been widely used to prevent tooth decay. Standard fluoride toothpaste, available to buy on the high street, contains around 1400 parts per million (ppm) of fluoride. High dose fluoride toothpaste, containing 5000ppm fluoride, is available by prescription from your dentist and is increasingly provided to patients judged to be at risk of decay.

In 2016 prescriptions of high dose fluoride toothpaste cost the NHS over £20 million and these costs are increasing rapidly. However, there is a lack of evidence to demonstrate that this toothpaste benefits patients and is cost-effective for the NHS.


The Reflect study aims to evaluate if prescribing high dose fluoride toothpaste can improve the dental health of older adults who have a high-risk of tooth decay, and reduce costs for both patients and the NHS. The study will run for 3 years and aims to recruit approximately 1200 people aged 50 years and over from NHS dental practices in Northern Ireland, Scotland and Greater Manchester. 
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Study news

Recruitment

1161/1174

Trial sites

Latest addition to sites:

Woodlands Dental Practice
Church Road Dental Practice
Remarkable Smiles (Pearl Dental)
Glumangate Dental Practice
Cottage Dental Practice {my}dentist
Hafren House Dental Practice
Alyth Dental Care
Simply Smiles Dental Surgery
Kirkmuirhill Dental Practice
Ethos Dental Care
Truss Dental
Maryhill Smile Care
Tarbert Dental Surgery
Abbey Dental Clinic
Montgomery Street Dental Care
Abbey Dental Care
PCK Wee Dental Surgery
Delicate Dental
Sankey Street Dental Practice
Clark & Watson Dental Practice
The Collegiate Dental Practice
Canmore Dental Practice (Lochgelly)
Hyland Dental Care
Canmore Dental Practice (Dunfermline)
Sheil Road Dental Practice
The Dental House
Castlebawn Dental Practice
Rankin Dental
Stevenston Cross Dental
Craigentinny Dental Practice
Harpers Dental Practice
Tannochside Dental (mydentist)
Dental Bees
The Glens Dental Practice
Cardonald Dental Practice
Livingston Dental Healthcare
Blairgowrie Dental Care
Camlough Dental Practice
Quinn dental
L.C. Milton BDS
Haugh Dental Care
One Dental
Discovery Dental Care
Montrose Dental Practice
Bute Dental Surgery
Lossie Dental Practice
Kelvingrove Dental Care Ltd
Main Street Dental Care
Newcastle Family Dental Care
The Grange Dental Care
Bishop Street Dentalcare
Bell & Thom Dental Surgery
DJ Maguire & Associates
Brownlow Family Dental Care
North Street Dental Care

Contact Us

If you have any questions

Participating Centres

North Street Dental Care

Key people:

Investigator:

  • Mr Christopher Minnis

Address:

42 North Street
Lurgan
BT67 9AH
Brownlow Family Dental Care

Key people:

Investigator:

  • Ms Catherina Beatty

Address:

5 Legahory Centre
Legahory
Craigavon
BT65 5BE
DJ Maguire & Associates

Key people:

Investigator:

  • Ms Heather Topping

Address:

83a Bridge Street
Portadown
BT63 5AA
Bell & Thom Dental Surgery

Key people:

Investigator:

  • Mr Andrew Bell

Address:

17/19 Main Street
Portglenone
Ballymena
BT44 8AA
Bishop Street Dentalcare

Key people:

Investigator:

  • Mr Gerard Cleary

Address:

21 Bishop Street
Londonderry
BT48 6PR
The Grange Dental Care

Key people:

Investigator:

  • Mr Paul Grugan

Address:

2 Crevenagh Road
Omagh
Co Tyrone
BT79 0AL
Newcastle Family Dental Care

Key people:

Investigator:

  • Mr David Knowles

Address:

2 Iveagh Court
Railway Street
Newcastle
BT33 0SP
Main Street Dental Care

Key people:

Investigator:

  • Mr Hari Shakar Lal

Address:

45a Main Street
Thornliebank
Glasgow
G46 7SF
Kelvingrove Dental Care Ltd

Key people:

Investigator:

  • Ms Anne Craig

Address:

1180 Argyle Street
Glasgow
G38TE
Lossie Dental Practice

Key people:

Investigator:

  • Mr Javier Margallo

Address:

2 Clifton Road
Lossiemouth
IV31 6DJ
Bute Dental Surgery

Key people:

Investigator:

  • Mr Cameron McLarty

Address:

14-16 West Princes Street
Rothesay
Isle of Bute
PA20 9AF
Montrose Dental Practice

Key people:

Investigator:

  • Ms Lorraine Arnot

Address:

53 John St
Montrose
DD10 8LZ
Discovery Dental Care

Key people:

Investigator:

  • Ms Avril Aitken

Address:

1 West Bell Street
Dundee
DD1 1EX
One Dental

Key people:

Investigator:

  • Ms Deirdre Ball

Address:

1 Queen Street
Londonderry
BT48 7EF
Haugh Dental Care

Key people:

Investigator:

  • Mr Andrew Haugh

Address:

3-5 Newcastle St. Kilkeel
Newry
County Down
BT34 4AF
L.C. Milton BDS

Key people:

Investigator:

  • Mr Lindsay Milton

Address:

1356 Barhead Rd
Glasgow
G53 7DE
Quinn dental

Key people:

Investigator:

  • Mr Liam Quinn

Address:

53 Main Street
Randalstown
Antrim
BT41 3BB
Camlough Dental Practice

Key people:

Investigator:

  • Mr Billy Campbell

Address:

27 Main Street
Camlough
Newry
County Down
BT35 7JG
Blairgowrie Dental Care

Key people:

Investigator:

  • Mr Stewart McLean

Address:

64 High Street
Blairgowrie
PH10 6DF
Livingston Dental Healthcare

Key people:

Investigator:

  • Mr Ross Livingston

Address:

38 Hamilton Road
Bangor
BT20 4LE
Cardonald Dental Practice

Key people:

Investigator:

  • Ms Helen Price

Address:

5 Lamington Road
Cardonald
Glasgow
G52 2SF
The Glens Dental Practice

Key people:

Investigator:

  • Mr Mark Morris

Address:

2 Gortaclee Road
Cushendall
BT44 0TE
Dental Bees

Key people:

Investigator:

  • Ms Lina Petrauskyte

Address:

1 St. Andrew Street
Castle Douglas
DG7 1DE
Tannochside Dental (mydentist)

Key people:

Investigator:

  • Ms Maureen Henderson

Address:

499 Old Edinburgh Road
Tannochside
Glasgow
G71 6PL
Harpers Dental Practice

Key people:

Investigator:

  • Mr David Harper

Address:

32 Bradford Street
Bolton
BL2 1JJ
Craigentinny Dental Practice

Key people:

Investigator:

  • Ms Miriam Figge

Address:

57 Duddingston Crescent
Edinburgh
EH15 3AY
Stevenston Cross Dental

Key people:

Investigator:

  • Ms Alison Livingston

Address:

14 Fullarton Place
Stevenston
Ayrshire
KA20 3EH
Rankin Dental

Key people:

Investigator:

  • Mr Stephen Rankin

Address:

30 Ellon Road
Bridge of Don
Aberdeen
AB23 8BX
Castlebawn Dental Practice

Key people:

Investigator:

  • Ms Julie Robinson

Address:

32-34 Victoria Road
Bangor
County Down
BT20 5EX
The Dental House

Key people:

Investigator:

  • Mr Stuart Garton

Address:

6-10 Derby Lane
Old Swan
Liverpool
L13 3DL
Sheil Road Dental Practice

Key people:

Investigator:

  • Mr Steven Korb

Address:

74 Sheil Road
Liverpool
L6 3AF
Canmore Dental Practice (Dunfermline)

Key people:

Investigator:

  • Ms Aleks Wasiak

Address:

8 Abbey Park Place
Dunfermline
KY12 7PD
Hyland Dental Care

Key people:

Investigator:

  • Mr John Hyland

Address:

6 Park Road
Hamilton
ML3 6PD
Canmore Dental Practice (Lochgelly)

Key people:

Investigator:

  • Mr Alan Torgersen

Address:

126 Main Street
Lochgelly
KY5 9AA
The Collegiate Dental Practice

Key people:

Investigator:

  • Mr Michael Somerville

Address:

76 Brideoak Street
Cheetham Hill
Manchester
M8 0AB
Clark & Watson Dental Practice

Key people:

Investigator:

  • Mr Alan Marshall

Address:

27 Newmarket Street
Falkirk
FK1 1JJ
Sankey Street Dental Practice

Key people:

Investigator:

  • Ms Mary Samuel

Address:

61a Sankey Street
Warrington
WA1 1SL
Delicate Dental

Key people:

Investigator:

  • Ms Monica O'Reilly

Address:

106 Main Street
Lisnaskea
County Fermanagh
BT920JD
PCK Wee Dental Surgery

Key people:

Investigator:

  • Mr Philip Wee

Address:

102a Cricklewood Broadway
London
NW2 3E5
Abbey Dental Care

Key people:

Investigator:

  • Ms Hazel Pahnke

Address:

47 Causeyside Street
Paisley
PA1 1YN
Montgomery Street Dental Care

Key people:

Investigator:

  • Mr Alex Coakley

Address:

96 Montgomery Street
Edinburgh
EH7 5HE
Abbey Dental Clinic

Key people:

Investigator:

  • Ms Jane O'Dowd

Address:

620-630 Shore Road
Newtonabbey
BT37 0ST
Tarbert Dental Surgery

Key people:

Investigator:

  • Ms Veronica Smith

Address:

Harbour Street
Tarbert
PA29 6UQ
Maryhill Smile Care

Key people:

Investigator:

  • Ms Sunita Lagoo

Address:

283 Maryhill Road
Maryhill
Glasgow
G20 7YA
Truss Dental

Key people:

Investigator:

  • Mr Richard Truss

Address:

85 East Road
Irvine
KA12 0AA
Ethos Dental Care

Key people:

Investigator:

  • Mr Simon Li

Address:

126 Wellington Road
Stockport
Cheshire
SK4 2LL
Kirkmuirhill Dental Practice

Key people:

Investigator:

  • Mr Piotr Prosowski

Address:

14a Thornton Road
Kirkmuirhill
ML11 9QE
Simply Smiles Dental Surgery

Key people:

Investigator:

  • Ms Sharon Benton

Address:

35 Holden Road
Salford
M& 4LR
Alyth Dental Care

Key people:

Investigator:

  • Ms Amy Anderson

Address:

20 Commercial Street
Alyth
PH11 8AF
Hafren House Dental Practice

Key people:

Investigator:

  • Mr Bhupinder Dawett

Address:

1 Cressy Road
Alfreton
Derbyshire
DE55 7BR
Cottage Dental Practice {my}dentist

Key people:

Investigator:

  • Ms Wendy Thompson

Address:

6-8 Chapel Lane
Kirby Lonsdale
Carnforth
LA6 2AL
Glumangate Dental Practice

Key people:

Investigator:

  • Mr Rami Khatib

Address:

46 Glumangate
Chesterfield
S40 1TX
Remarkable Smiles (Pearl Dental)

Key people:

Investigator:

  • Mr Amit Koshal

Address:

1242 London Road
Alvaston
Derby
DE24 8QH
Church Road Dental Practice

Key people:

Investigator:

  • Ms Nicola Keogh

Address:

66 Church Road
Bebington
Wirral
CH63 3EB
Woodlands Dental Practice

Key people:

Investigator:

  • Mr James Ashley

Address:

493 Old Chester Road
Rock Ferry
Wirral
CH42 4NG

Key facts about the study and documents

Recruitment of participants to the REFLECT study finished in March 2020 and the study is now in follow-up. There are 60 dental practices across Scotland, Northern Ireland and England taking part in REFLECT and 1161 participants recruited to the study. Thank you to all who have agreed to take part.

When you consented to take part in REFLECT you were randomised to receive either a prescription for 5000ppm fluoride toothpaste or to receive the usual care and advice on buying and using standard fluoride toothpaste.

You should continue to attend your dental practice for regular check-ups as usual during the 3-year follow up, where your dentist will examine your teeth and gums, record information about your dental health and prescribe high dose fluoride toothpaste for those participants that were randomised to receive this as part of the study. You will also be asked to complete confidential questionnaires each time you attend your dental practice and sent annually to your home address.

Your contribution to the study is valuable for the integrity of the study and important for the results of REFLECT. Both groups of participants (those prescribed high fluoride toothpaste and those not) will be followed up for 3 years so that at the end of the study any difference in dental health and the costs of dental care between the 2 groups can be compared. All information collected about you during the course of the research will be kept confidential. The results will be used to make recommendations about treatments for patients with a risk of tooth decay and published in scientific journals.

We welcome any feedback or questions about the REFLECT study by emailing the coordinating team at REFLECT@dundee.ac.uk.

You can find out more information about REFLECT here:

Key contacts

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Organisation

The Reflect study is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (project: 16/23/01) . For more information please visit www.nets.nihr.ac.uk.

General Data Protection Regulation (GDPR)
Participant Information

Manchester University NHS Foundation Trust is the sponsor for this study based in the United Kingdom. We will be using information from you and your dental records in order to undertake this study and will act as the data controller for this study. This means that we are responsible for looking after your information and using it properly. Manchester University NHS Foundation Trust will keep identifiable information about you for up to 15 years after the study has finished.

Your rights to access, change or move your information are limited, as we need to manage your information in specific ways in order for the research to be reliable and accurate. If you withdraw from the study, we will keep the information about you that we have already obtained. To safeguard your rights, we will use the minimum personally-identifiable information possible.

You can find out more about how we use your information by contacting information.governance@mft.nhs.uk.